Ginipral during pregnancy - description and reviews. What helps ginipral during pregnancy: why is the drug prescribed? Can ginipral

As part of one pills is 500 mcg hexoprenaline sulfate + lactose hydrate, disodium edetate dihydrate, talc, glycerol palmitate stearate, corn starch, copovidone, magnesium stearate.

AT solution for intravenous administration active ingredient per 1 ml - 5 mcg + disodium edetate dihydrate, diluted sulfuric acid, sodium pyrosulfite, sodium chloride, water for injection.

Release form

The medicine is released in tablets, in blisters of 10 pieces each, in a cardboard box 2 blisters. Tablets are white, round, convex.

It is also available in the form solution for injection in ampoules of 2 ml, in contour plastic packs of 5 pieces, in cardboard packs of 1 or 5 packs.

pharmachologic effect

Tocolytic.

Pharmacodynamics and pharmacokinetics

Hexoprenaline - selective beta-2-sympathomimetic, consisting of two catecholamine groups. The active substance has the ability to block specific receptors of the uterus and relax its muscles. The frequency and intensity of contractions is significantly reduced. The medicine blocks labor pains ( spontaneous or arising under the influence of a hormone).

During childbirth, Ginipral can normalize the strength and regularity of uterine contractions and inhibit premature contractions. The drug, in those who took during pregnancy, allowed the fetus to be carried to a normal term. The drug has the ability to slightly affect CCC pregnant woman and fetus.

Immediately after intravenous administration of the drug, the inhibition of contractions begins, the effect of the drug continues for about 20 minutes.

After entering the body, the active substance undergoes methylation via catecholamine-o-methyltransferase . It is noteworthy that the process methylation only one of the catecholamine groups otherwise hexoprenaline become biologically inactive. Therefore, the tool has a rather long effect on the body.

In the first 4 hours after taking the drug, about 80% of the active components of the drug are excreted in the urine. A small amount of the drug is excreted in the bile in the form.

Indications for use

Tablets are prescribed for the existing threat of premature birth, including as part of complex treatment.

The use of injections and droppers is shown:

  • before the coup of the fetus (if necessary, coup);
  • with a clear or hidden prolapse of the umbilical cord or its entanglement;
  • for immobilization of the uterus before ;
  • as an emergency measure if preterm labor occurs, before taking the woman to the honey. institution;
  • during inhibition of contractions during childbirth (with acute intrauterine );
  • to slow down premature contractions if the cervix is ​​open or the cervix is ​​flattened;
  • for the prevention of premature contractions;
  • during the cervical cerclage for immobilization of the uterus.

Contraindications

The drug is not prescribed:

  • with heart and high blood pressure;
  • women suffering from severe kidney and liver diseases;
  • at ;
  • at ;
  • in the first trimester of pregnancy;
  • in violation of the heart rhythm, myocarditis ;
  • persons with mitral valve disease or aortic stenosis ;
  • at ;
  • when on the components of the product (especially on sulfites );
  • during the period ;
  • with intrauterine infections and bleeding, premature placental abruption .

Side effects

As a rule, there are no problems when using this tool.

During the reception, anxiety, nausea, may develop.

Instructions for Ginipral (Method and dosage)

Depending on the task and the condition of the pregnant woman, various dosage forms are used in various dosages.

Application instruction of Ginipral in tablets

The tablet is swallowed whole with water.

As a rule, the medicine is prescribed one tablet every 3 hours, then the interval between doses is reduced to 4-6 hours. The average daily dosage is from 2 to 4 mg of the drug (up to 8 tablets).

If there is a threat of preterm labor, then the drug is taken at a dosage of 500 mcg 60-120 minutes before the end of the infusion hexoprenaline .

Ginipral infusion during pregnancy

The dosage is selected individually, after consultation with the doctor.

The contents of one capsule are usually diluted in isotonic solution sodium chloride . Enter slowly, gradually, for 5-10 minutes.

  • at acute toxolysis make an intravenous injection of 10 mcg of the drug, then switch to infusion;
  • during massive toxolysis one ampoule (2 ml) is used, the average rate of administration is 0.3 micrograms per minute;
  • at prolonged toxolysis the dosage is selected by the doctor, the rate of administration is 0.075 mcg per minute.

If after 2 days the contractions have not resumed, then they switch to the tablet form.

Overdose

With an overdose, pronounced tachycardia , dizziness , headache and may decrease, develop anxiety and .

Interaction

Do not mix in one syringe (dropper) Ginipral and other solutions except isotonic solution and glucose .

Beta blockers neutralize or significantly weaken the effect of the drug.

The drug weakens the effect hypoglycemic drugs.

Methylxanthines , in particular Theophylline, can enhance the effectiveness of the tool.

It is not recommended to combine the drug with sympathomimetics , beta-agonists and halothane due to the increased burden on cardiovascular system .

Combination glucocorticosteroids Ginipral can reduce the intensity of accumulation processes in the liver glycogen .

Ginipral during pregnancy

Reception of funds in the first 12 weeks is prohibited.

The use of droppers during pregnancy is indicated in the 2nd and 3rd trimesters. Injections should be made under the supervision of a physician.

Pills are often prescribed during late pregnancy, to reduce the likelihood of preterm birth with uterine hypertonicity .

Taking medication during lactation is highly discouraged.

Judging by the reviews, sometimes side effects from the drug appear, so you can drink it only after consulting a doctor.

Instructions on how to take Ginipral tablets during pregnancy are described above.

It should be added that doctors often prescribe Ginipral during pregnancy (in combination). Thus, it is possible to avoid the manifestation of side effects from both agents.

Despite the fact that many women prepare for conception in advance and under the supervision of doctors, there are always risks of complications. The most common pathology is hypertonicity of the smooth muscles of the walls of the uterus. The condition is characterized by a chaotic contraction of muscles that are in constant tension.
Hypertonicity is fraught with miscarriage and premature birth. Tense muscles of the uterus do not allow to fully supply the developing fetus with oxygen and nutrients. Prolonged hypoxia and starvation leads to pathologies in the development of the child.

Ginipral during pregnancy is an effective drug for relaxing the myometrium of muscle tissue and reducing pressure in the uterine cavity.

The drug is produced in tablet form and capsules for intravenous administration. The price of a blister (20 tablets) ranges from 170 to 200 rubles. A package for intravenous administration, consisting of 5 ampoules, costs 250–300 rubles.

The main active ingredient in Ginipral tablets is gescoprenaline sulfate.

Excipients: disodium edetate dihydrate, copovidone, magnesium stearate, lactose hydrate, corn starch and talc.

During pregnancy, Ginipral tablets should be guided by the instructions and recommendations of the attending physician. With the threat of miscarriage, the drug is prescribed one tablet (500 mcg) with an interval of three hours, regardless of the meal.

After stopping the acute stage and stabilizing the condition, the time period is increased to 4-6 hours, gradually reducing the dosage (1-2 tablets per day).

Ginipral for intravenous administration is available in glass ampoules, which contain 2 ml of a ready-made solution with an active substance content of 10 μg. As auxiliary agents, the solution contains: 2H-sulfuric acid, sodium chloride, sodium pyrosulfate, deionized water.

The drug is administered by jet or drip method intravenously in critical situations when there is a threat of abortion. The contents of two ampoules are diluted in 5% glucose or sodium chloride solution. A few hours before the end of invasive therapy, the drug is prescribed in tablet form.

It must be remembered that the dosage of Ginipral during pregnancy is selected individually, after a thorough examination and study of the anamnesis.

When to cancel Ginipral during pregnancy? A very important issue for the health of the mother and baby. When using a high dosage after achieving a therapeutic effect, the amount of the drug is reduced.

Abrupt withdrawal causes hypertonicity of the muscles of the walls of the uterus, which can lead to miscarriage or premature birth. In order to avoid negative consequences, the abolition of Ginipral during pregnancy takes place in stages, the dosage of the drug is reduced, and the intervals between doses are increased.

The mechanism of action of the drug

Hexoprenaline is a tocolytic and selective beta2-adrenergic stimulant.

The tocolytic effect is manifested in the relaxation of the vessels of the placenta and myometrium. Regular intake of the drug prevents the contraction of the walls of the uterus and eliminates its increased tone.

Under the influence of the drug, premature contractions stop, which allows you to carry a healthy baby and extend the pregnancy to physiological childbirth.

Often, together with Ginipral, Asparkam is prescribed. This is a time-tested drug for regulating metabolic processes, restoring electrolyte balance, a source of magnesium and potassium. It is a physiological blocker of slow calcium channels.

Potassium and magnesium are necessary to maintain cardiac activity and antiarrhythmic action when taking Ginipral.

The lack of minerals leads to muscle excitability and increased muscle activity. Ginipral and Asparkam during pregnancy are an excellent combination and are prescribed for increased uterine tone.

Indications for use

Ginipral tablets during pregnancy and intravenous injections are proven drugs and are widely used in obstetric practice. They are used for the threat of premature birth or miscarriage caused by various factors.

Indications for use are:

  • the need to produce obstetric rotation of the fetus with a transverse or oblique presentation;
  • premature contractions;
  • the need to relax the walls of the uterus before a caesarean section;
  • pronounced contractile activity of the uterus.

The drug is actively used as an aid during labor to normalize the intensity of contractions.

Side effects

Side effects of Ginipral during pregnancy are well studied and described by the medical community. If the drug is used for the first time, then the woman should carefully monitor her well-being in order to take timely measures.

After taking the drug, the following phenomena may occur:

  • nausea and dizziness;
  • elevated blood glucose levels;
  • headache;
  • a sharp drop in blood pressure;
  • tremor of the limbs;
  • increased sweating;
  • heart palpitations;
  • swelling and diuresis (urinary retention).

Given the possible side effects, treatment is carried out under the supervision of a physician with monitoring of blood pressure, cardiac activity and blood sugar. To eliminate tachycardia and heart pain, Finoptin is prescribed 30-60 minutes before taking the main drug.

With difficulty breathing and severe heart pain, the drug is canceled. In most cases, Ginipral is tolerated without side effects or with a slight discomfort that can be easily corrected.

Contraindications

How to use Ginipral during pregnancy, only the doctor decides. With caution, the drug is prescribed for diabetes mellitus.

It is advisable to limit the intake of salt and liquids. Drinks containing caffeine may increase the side effects of the medication.

During the bearing of the baby, the hemodynamic parameters of the expectant mother and fetus are constantly monitored, and the fetoplacental complex is assessed.

Absolute contraindications for taking Ginipral are:

  • hypersensitivity to sulfites (especially in patients with allergies and bronchial asthma);
  • cardiovascular diseases, including heart defects and ischemic disease;
  • kidney and liver diseases;
  • first trimester of pregnancy;
  • breast-feeding;
  • thyrotoxicosis;
  • sexual infections.

Interaction with other drugs and special instructions

It is important to remember that when exposed to calcium preparations, vitamin D and non-selective beta-blockers, the effect of Ginipral is neutralized.

During the period of use of the drug, constant monitoring of cardiac activity and blood pressure is recommended. In case of rupture of the amniotic membrane and dilatation of the cervix by more than 2-3 cm, the chances of the effect of tocolytic therapy are negligible.

Analogues

Ginipral during pregnancy is an indispensable drug to prevent premature birth. Analogues are Ipradol and Partusisten. In terms of effects, the drugs are close to Ginipral, but they have fewer side effects.

The experience of using analogs shows that drugs are effective and do not adversely affect the condition of the woman in labor and the newborn.

Prevention of uterine hypertonicity

With increased tension of the smooth muscles of the walls of the uterus, the expectant mother needs peace, a comfortable psychological environment and timely intake of drugs that relieve spasm. For the entire period of treatment, a taboo is imposed on sexual contacts.

Most of the time, a woman should be in a supine position. You can put a roller under your legs, which will reduce the tension of the abdominal press.

It is important to start treatment of chronic diseases in a timely manner and refuse to visit crowded places, including work. Moderate walking in comfortable shoes without heels is recommended.

The expectant mother needs to include foods containing magnesium in the daily menu. The trace element helps to reduce uterine hypertonicity, reduces the excitability of the nervous system. Magnesium is found in bran, buckwheat, oatmeal, legumes and greens.

To avoid complications, prepare for conception and childbearing in advance. Treat the recommendations of a doctor with increased responsibility, observe the daily routine and maintain a positive psychological attitude.

It is important to remember that the appointment and administration of Ginipral is carried out only by the attending physician in a specialized clinic. Self-medication is unacceptable and can cause irreparable harm to the health of the mother and baby!

Useful video about increased uterine tone

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Ginipral refers to drugs that reduce the tone and contractile activity of the uterus, that is, it has a relaxing effect on the uterus. Such drugs are called "tocolytics" - means to prevent premature birth.


The uterus is a muscular organ that can contract. During a normal pregnancy, muscle fibers are in a relaxed state, contractions begin with the arrival of the term of delivery. There are many factors that contribute to the development of increased uterine tone (hypertonicity). Hypertonicity is dangerous because it can cause abortion, as well as intrauterine hypoxia and retardation in the development of the fetus according to the results of ultrasound due to insufficient supply of oxygen and nutrients to the child.

Under the influence of Ginipral, premature contractions in most cases stop, which allows you to extend the pregnancy until the normal term of delivery. Reducing the frequency and intensity of uterine contractions improves uteroplacental blood flow, resulting in an increase in the oxygen concentration in the blood of the fetus, which prevents fetal hypoxia. During childbirth, Ginipral normalizes excessively strong or irregular contractions.

The use of Ginipral during pregnancy

Ginipral is prescribed by an obstetrician-gynecologist with the threat of spontaneous miscarriage, placental insufficiency, uterine hypertonicity starting from the 20th week of pregnancy, and also to prevent premature birth (tocolytics can delay labor by at least 48 hours).

Ginipral is administered to pregnant women inside in the form of tablets, and in a hospital, Ginipral is administered by intravenous infusion.

Contraindications to the use of Ginipral

  • first trimester of pregnancy (up to 20 weeks);
  • bleeding from the vagina of any origin, premature detachment of the placenta; intrauterine infections;
  • diseases of the heart and blood vessels, especially cardiac arrhythmia, occurring with tachycardia, myocarditis, coronary heart disease (CHD);
  • individual intolerance (especially for patients suffering from bronchial asthma);
  • thyrotoxicosis (excess thyroid hormone);
  • severe liver and kidney disease;
  • lactation period (breastfeeding);
  • patients with lactose intolerance

Side effects and warnings when using Ginipral

Before starting treatment with Ginipral, it is necessary to conduct an ECG control of the pregnant woman. While taking Ginipral, a pregnant woman may experience dizziness, headache, heart palpitations (tachycardia), weakness, slight tremor (trembling) of the fingers, and increased sweating. There may be a decrease in blood pressure.

Ginipral, like other tocolytics, can cause an increase in plasma glucose levels and a decrease in potassium levels. Ginipral is incompatible with preparations containing calcium and vitamin D. During treatment with hypipral, you should stop drinking tea and coffee, as these drinks can increase the side effects of the drug. Under the influence of Ginipral, diuresis (the amount of urine excreted) decreases, therefore it is very important to monitor the symptoms showing fluid retention in the body, for example, swelling of the lower extremities (legs), especially if the pregnant woman has a concomitant kidney disease, preeclampsia, detection of protein in the urine (proteinuria ). Strictly limit excess fluid intake (no more than 2 liters per day) and reduce salt intake as much as possible.

Blood pressure, pulse and cardiac activity (HR) should be under constant medical supervision. With an increase in the heart rate of a pregnant woman (more than 130 beats / min) or with significant fluctuations in blood pressure, the dose of the drug must be reduced. With the appearance of compressive pain in the heart and difficulty breathing, you should immediately stop taking the drug and inform your doctor about it. When taking Ginipral, it is desirable to conduct CTG to clarify the condition of the fetus and the tone of the uterus.

Pregnant women with diabetes should regularly monitor their blood sugar levels. Due to the content of lactase, Ginipral is not recommended for pregnant women who have lactose intolerance.

How to use Ginipral during pregnancy

Ginipral in tablets of 0.5 mg is administered orally, without chewing and with a small amount of water. The doctor selects the dosage individually, taking into account the tolerability of the drug. Initially, 1 tablet is prescribed every 3 hours, and then every 4-6 hours (from 4 to 8 tablets per day). In case of poor tolerance, the drug is used in reduced doses prescribed individually (half or even a quarter) and under constant medical supervision.

Ginipral and Verapamil

The most common side effect that pregnant women experience when taking Ginipral is heart palpitations (feeling that the heart will jump out of the chest). To eliminate side effects to Ginipral, the doctor may prescribe Verapamil (a calcium antagonist), which not only relieves side effects, but also suppresses the contractile activity of the uterus.

Therefore, Verapamil and Ginipral during pregnancy are most often prescribed together - one drug inhibits the strong effect of the other. Verapamil is taken 20 minutes before taking Ginipral.

Verapamil is an international non-proprietary name with the active substance - verapamil hydrochloride. This category of medicines also includes: Finoptin, Isoptin.

The list of medicines is given for informational purposes and is not intended for self-treatment.

Complications during pregnancy are unpredictable. One of the dangerous conditions is uterine hypertonicity, in which there is a threat of miscarriage or premature birth. In a similar situation, women are prescribed the drug ginipral - intravenously or in the form of tablets.

Uterine tone

The uterus during gestation should be in a relaxed state, however, its functioning may be impaired. What is uterine hypertonicity? In this condition, the muscles contract either continuously or intermittently. Why is this happening? Hypertonicity of the uterus may be due to psychological reasons:

  • inactive lifestyle;
  • bad habits of the expectant mother;
  • stress and excessive hassle;
  • other reasons.

A pregnant woman should get enough sleep and not overexert herself. Chronic sleep deprivation can cause unplanned uterine muscle contractions. Harmful influences on the tone of the uterus include unfriendly relationships in the family, early abortions and early pregnancy (up to 18 years). Also, hypertonicity can occur in women after 35 years of age during their first pregnancy. Unfavorable factors include influenza, SARS during gestation, and a history of inflammatory processes.

Also, hypertonicity can be caused by physiological reasons:

  • malformations;
  • multiple pregnancy;
  • endometriosis of the uterus;
  • uterine myoma;
  • somatic diseases;
  • genetic feature;
  • immune deficiency;
  • endocrine diseases.

Until the four-week gestation period, this pathology is treated with hormonal drugs. At a later date, ginipral is prescribed - intravenously or in tablets. Also, the drug is prescribed during labor with uneven and too intense contractions.

Survey

Untimely contraction of muscle fibers is fraught not only with miscarriage, but also with oxygen starvation of the fetus. Such a pathology affects the normal development of the fetus, prevents the intake of nutrients and can cause irreversible changes.

For a woman, muscle contraction can cause pain, cause spotting, and make you feel unwell. How to independently determine hypertonicity? Symptoms of this pathology are:

  • cramping abdominal pain;
  • drawing pains in the base of the back;
  • a characteristic feeling of tension in the abdomen;
  • "petrification" of the abdomen.

If these signs are accompanied by bloody or brown discharge, the pathology is obvious. An urgent examination is needed, after which the doctor will prescribe ginipral tablets / intravenously.

Medical diagnostic methods include:

  1. vaginal examination;
  2. hardware research.

Important! Drawing pain in the abdomen is not a symptom of a complication. Pathology is accompanied by other signs of disease or abnormality. Pain in the first half of pregnancy may be due to the growth of the uterus.

Prescribing the drug

Ginipral is prescribed after the 20th week of pregnancy in case of pathology. Tablets are drunk to prevent uterine contractions, a dropper is placed in case of emergency assistance with the threat of miscarriage. The drug in the form of tablets is taken for a long course of up to two months. In case of improvement in muscle condition, the dosage of the drug is adjusted.

Important! It is forbidden to use the drug ginipral alone during pregnancy without consulting a gynecologist.

The course of therapy is calculated individually. Sometimes the uterus returns to normal after a month of taking the drug, sometimes treatment is required for the entire second half of pregnancy. It depends on the individual state of the woman's organ and the characteristics of the course of pregnancy. With the normalization of the tone of the uterus, the drug is gradually reduced in dosage.

Important! It is forbidden to abruptly stop the use of ginipral in order to avoid recurrence of the complication.

During the course of treatment with Ginipral, the state of the pulse and blood pressure of the woman and fetus should be checked. The doctor prescribes an electrocardiogram to check the mother's cardiac activity, and CTG is performed to monitor the condition of the fetus. With an increase in the woman's pulse, the dosage of the drug is reduced.

Important! The drug ginipral increases blood glucose, so chronic diabetics should measure their sugar levels regularly.

The introduction of the drug during pregnancy reduces the amount of urine excreted. This is normal. You should not get carried away with liquids to increase the rate of excreted urine: you need to consume liquid in a volume of 2.5 liters in essence.

With the appearance of shortness of breath and disruption of the heart, the drug is immediately canceled. This may be an indicator of a drug overdose. Overdose symptoms are:

  • arrhythmia and tachycardia;
  • intense sweating;
  • trembling of the fingers;
  • pressure drop;
  • heartache;
  • headaches.

To eliminate an overdose, antagonists are used - drugs that eliminate the effect of ginipral. These funds are prescribed by the attending gynecologist.

The action of the drug and side effects

The effectiveness of the drug ginipral decreases when interacting with certain medical agents. Ginipral is not prescribed simultaneously with beta-blockers. An increase in the effect of this drug was also noted when taken together with Theophylline.

The drug reduces the effectiveness of drugs against high blood sugar. When combined with bronchodilators, it produces side effects. Side effects include:

  • dizziness and pain in the head;
  • decreased bowel tone (constipation);
  • intestinal obstruction;
  • swelling and decreased urine;
  • active sweating;
  • anxiety and sleep disturbance;
  • disruption of the heart;
  • trembling of the fingers.

Also, side effects can be noted in the newborn: bronchospasm, acidosis, etc. Sometimes there is a decrease in labor activity in women in labor who took this drug: they are prescribed stimulation or caesarean section. However, complications in labor activity are also found in women who did not take ginipral.

Important! Do not drink ginipral tablets with coffee or strong tea in order to avoid increased side effects from the reaction to the drug substances.

Contraindications

In some cases, the appointment of the drug ginipral is prohibited. These include:

  • toxic goiter and Graves' disease;
  • myocarditis and arrhythmia of the heart muscle;
  • malformations and ischemic heart disease;
  • high blood pressure;
  • chronic liver / kidney disease;
  • uterine bleeding;
  • genital infections;
  • pathology of the placenta;
  • allergy to the components of the drug.

Also, the prohibition of prescribing the drug applies to the first trimester of pregnancy and the period of breastfeeding.

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Nine months of pregnancy is considered to be one of the happiest periods of life for every mother. This is undoubtedly true if the bearing of a child goes smoothly and without complications, which, unfortunately, can appear even out of the blue.

The state of pregnancy can be affected simply by a change in mood, not to mention those cases when the child was not planned and the whole period passes "on the nerves". In some cases, Ginipral is prescribed to relieve negative symptoms.

General information - description and properties

Ginipral in pharmacies is sold in the form of tablets and solution for droppers. This is a drug from the group of tocolytics - it is prescribed for spontaneous muscle contractions for a general relaxing effect on the muscles and blood vessels. Most often it is used during pregnancy with a diagnosis "uterine hypertonicity", less often - if necessary, perform an operation on this organ.

The drug completely removes the muscle contractions that have already begun, allowing the child to be carried until the moment when he is ready for childbirth, both in the usual way and through a caesarean section.

The main active ingredient is the substance hexoprenaline, which has a persistent effect on the muscles of the uterus. It is quickly absorbed into the blood and begins to act. Decay products are excreted from the body with urine and bile.

The complex effect of the drug relieves uterine hypertonicity and significantly reduces the risk of premature labor pains.

Tablets and dropper: what is included

The active substance in each tablet contains 500 mg of hexoprenaline sulfate. The tablets themselves are round, biconvex, white, sold in packs of 20 pieces.

The shell of Ginipral consists of the following excipients:

  • Glycerol palmitate stearate;
  • Disodium edetate dihydrate;
  • Copovidone;
  • Corn starch;
  • lactose hydrate;
  • magnesium stearate;
  • Talc.

For administration in the form of droppers, Ginipral is produced in two versions - this is a standard solution, ready for use, and a concentrate, which must be diluted with distilled water. Both options are 2 ml of a clear, colorless liquid containing the active substance of the drug - hexoprenaline. In solution it is 10 mg, and the concentrate contains 25 mg.

Excipients used:

  • Water deionized;
  • Disodium edetate dihydrate;
  • Sodium pyrosulfate;
  • Sodium chloride;
  • Sulfuric acid;

The acidity (pH) of all components of the solution is stabilized for the human body.

Indications for use during pregnancy

Prerequisites for the appointment of Ginipral may be the following diagnoses:

  • The tone of the uterus is increased. Her muscles become stiff, which is palpable by ordinary palpation. This condition is dangerous even in the early stages - uterine spasms cannot compress the fetus, but they cause vascular contractions, which impairs the supply of food and oxygen to the child.
  • Premature uterine contractions. If the due date has not yet arrived, then this can harm the fetus, since it has most likely not yet turned into the desired position.
  • Threat of fetal death.
  • If there is a risk of premature onset of labor.
  • If the birth takes place on time, but the contractions are too intense and irregular. Such cases are rare, but if you do not "calm" the uterus, then the likelihood of birth injuries increases.

Ginipral is prescribed exclusively in the second trimester of pregnancy. By this time, receptors are formed in the muscles of the uterus, which can perceive the action of the active substance. Until this time, its reception is useless, therefore, even with clear symptoms, other drugs will be selected.

How to take Ginipral during pregnancy: instructions, dosage


Ginipral is a drug that, if used incorrectly, can cause irreparable harm to the course of pregnancy - the health of the mother and child. The need for its use, the number of tablets per day and how often they should be taken, is decided only by the doctor, after examination and on the basis of the tests performed.

It is not surprising if Ginipral is prescribed to two patients with the same symptoms in the same ward, but the number of tablets and the frequency of taking them will vary significantly. The instructions for the drug contain recommended values, which say that the maximum possible number of tablets per day is 4 pieces.

The doctor, focusing on the indicators, can prescribe both 6 and 8, using individual schemes: a quarter, a third, half or a whole tablet; with a multiplicity of reception up to 3-4 hours. The doctor determines the therapeutic regimen necessary in this particular case depending on many factors, therefore there is no single method of administration.

What is known for sure is that at the time of taking the drug, you must abandon any drinks and foods containing caffeine, as it will increase the side effects of taking the medication.

Droppers with a solution are used in case of a direct threat of abortion. If the muscles of the uterus are strongly spasmodic, the abdomen is hard when palpated and hurts, then these are indicators for identifying the patient in the hospital and starting intravenous administration of the drug. Subsequently, droppers are replaced with tablets.

The course of treatment can take a long time - in some cases until the very end of pregnancy. If the patient's well-being has improved, then the dosage can be reduced or the interval between taking the tablets can be increased. You can not abruptly stop taking Ginipral - this is almost a 100% probability of a sharp return of all symptoms and an increase in the risk of abortion.

When should Ginipral not be taken during pregnancy?

Before prescribing the drug, the doctor must make sure that:

  • There is no individual intolerance to individual components;
  • There is no hyperfunction of the thyroid gland, when an increased release of hormones occurs in the body;
  • No diseases of the cardiovascular system (otherwise it is necessary to additionally prescribe maintenance drugs)
  • Tremor or uterine spasm did not lead to bleeding

In any case, taking Ginipral during pregnancy should be accompanied by strict monitoring of the patient's condition. In diabetes, it is necessary to carefully monitor the level of sugar and it is advisable to be in the hospital at this time.

Side effects from taking Ginipral during pregnancy

Their list is quite extensive, which often scares patients. Here we must understand that this is a list of only possible consequences - it is not at all necessary that they will manifest themselves.

But you need to prepare for the following:


  • Increased heart rate and tachycardia.
  • An increase in blood sugar levels.
  • Nausea and vomiting.
  • Tremor of the limbs.
  • Dizziness and headaches.
  • Increased perspiration.
  • Increased level of anxiety.
  • Problems with urination (more often - a decrease in the amount)
  • “Washing out” of calcium and potassium from the body
  • Manifestations of allergic reactions

The likelihood of such side effects from Ginipral during pregnancy increases dramatically when drinking coffee in any form. It is also recommended to drink less liquid and not to abuse salty - you can provoke the appearance of edema.