Duphaston is utrogestan what. Duphaston or Utrozhestan - which is better? But the advantages of Duphaston are quite significant

For the expectant mother, the threat of miscarriage is a great danger. The most common cause is a low level of progesterone in the blood. In such a situation, the doctor prescribes an additional dose of the hormone, which is available in the form of Duphaston and Utrozhestan tablets.

The effect of progesterone on the female body

For a better understanding of the principle of action of Duphaston and Utrozhestan, it is worth understanding what progesterone is. Progesterone (the second name is “pregnancy hormone”) is classified as a progestogen. The adrenal glands, ovaries and placental tissues are responsible for its production. The hormone plays a serious role - it is responsible for preparing the uterine endometrium for the adoption of a fertilized egg. The most active progesterone works in the body in the second part of the cycle (in the absence of pregnancy) and directly in the 1st trimester of pregnancy. Due to the activity of the substance, gestation initially passes without complications in the form of a threat of miscarriage.

In the first three months of gestation, the corpus luteum of the ovaries is responsible for the release of the "hormone of pregnancy", which ensures the growth and development of the fetus and prevents the formation of the following eggs. Having completed the necessary, the corpus luteum ceases to perform this function, and before childbirth, the placenta, which has matured to this stage, is responsible for the production of the substance.

One of the factors of possible infertility is an insufficient level of progesterone in the female body. During the planning period of pregnancy, it is important to take an analysis for the hormone - the onset of ovulation and conception depend on it.

What to choose to normalize hormonal levels

Initially, it may seem that Dufaston and Utrozhestan are more similar to each other than they differ. But this is a misconception. Let's look at the features of each drug.

The composition of Utrozhestan includes natural progesterone, which is produced from components of plant origin. Its molecules are the same as those that the female body independently produces. Utrozhestan has an efficiency similar to natural progesterone.

Utrozhestan is prescribed in the following cases:

• infertility associated with hormonal disorders;
• the likelihood of miscarriage;
• frequent miscarriage;
• increase in the amount of male sex hormones;
• disruptions in the menstrual cycle;
• manifestations of mastopathy;
• uterine myoma.

The main active ingredient of Duphaston is dydrogesterone. It is a synthetic analogue of natural progesterone. But, regardless of the artificial nature, Duphaston is still almost identical to the natural “pregnancy hormone”, and the therapeutic effect of the application is quite good. When taking Dufaston, there are no side effects, the drug is safe for use during the period of bearing a baby.

• pregnancy planning by in vitro fertilization (IVF);
• the threat of miscarriage;
• syndromes during menopause as hormone therapy;
• disruptions in the menstrual cycle (amenorrhea, dysmenorrhea, PMS);
• endometriosis.

How to choose: Dufaston or Utrozhestan

Both drugs are substitutes for progesterone. Prescribing drugs, doctors usually focus on personal experience and the results of therapy already available. Consider the pros and cons of Duphaston and Utrozhestan.

Advantages of Duphaston over Utrozhestan:

• minimal likelihood of side effects (weakness, drowsiness);
• highly effective in case of pregnancy planning by IVF (the highest level of fetal survival);
• does not pose a danger to the child;
• reduces the likelihood of premature birth (fetoplacental insufficiency);
• does not contribute to the occurrence of acne, excessive hair growth and other male features if the unborn child is a girl;
• does not affect liver health.

Why Utrozhestan is better than Duphaston

• similar to natural hormone;
• does not contribute to the growth of body weight;
• does not increase pressure;
• does not rebuild the metabolism;
• works well with an excess of male hormones;
• prevents oxytocin from affecting the uterus;
• does not affect the baby, is not able to cause developmental pathologies;
• not only oral, but also intravaginal (the tablet is injected into the genital tract) administration of the drug is allowed.

In case of a threat of miscarriage, this method of using the drug is the most effective.

Side effects from drugs

Dufaston and Utrozhestan are actively used during pregnancy, but the drugs have some side effects.

The use of Utrozhestan can cause:

• increase in body temperature (up to 38 degrees);
• mild drowsiness;
• mood swings;
• dizziness.

The negative effect of taking Duphaston is expressed in an increase in the likelihood of uterine bleeding.

How to take pills

It has been proven that none of the remedies will negatively affect the ovulation process. It is forbidden to take Duphaston and Utrozhestan during breastfeeding.

Both drugs are taken under the strict supervision of a doctor according to a special scheme. If a woman regularly takes the drug, then it is not recommended to cancel it abruptly. Such inattention to health is fraught with miscarriage. Cancellation of the drug should be done in stages. For 3-4 weeks, the dosage is gradually reduced, and then the use is stopped (or another hormone therapy is prescribed).

In certain situations, funds are prescribed during the planning period of pregnancy. Then, after conception, taking Duphaston and Utrozhestan continues immediately until childbirth. The body gets used to the intake of progesterone from the external environment and stops producing the hormone naturally.

Contraindications to the use of drugs

The drug is able to be absorbed into the mother's milk, the medicine is not taken during breastfeeding.

Utrozhestan has more contraindications than Duphaston:

• bleeding from the genital tract of unknown origin;
• thrombophlebitis;
• hypertension;
• porphyria;
• incomplete abortion;
• malignant formations in the area of ​​the mammary glands and genital organs;
• congenital pathologies of the liver;
• allergic reactions to the components of the drug.

In case of the likelihood of developing thrombosis and disorders in the liver, the agent is used intravaginally. In the third trimester of gestation, tablets are prescribed in exceptional situations, at this time the liver is largely susceptible to any effects.

In special cases, doctors prescribe the simultaneous administration of two drugs. This method helps to reduce the risk of developing diseases associated with the use of hormonal drugs for a long time. In this case, it is possible to combine the intake of two drugs at once (Dufaston is prescribed orally, and in addition Utrozhestan - intravaginally). It is important to adhere to the regimen prescribed by the doctor.

The question of the correct choice of the drug should be decided by the attending physician, the decision of the specialist is based not only on the characteristics of the drug, but also on the personal characteristics of the body, the course of pregnancy, age, etc.

Remember: in the case of an attentive attitude to yourself and following the advice of a doctor, the process of carrying a baby and childbirth will be easy and without complications.

Reviews of members of the forum

Greetings, my dear readers! Today I will tell you one of the topics that often pop up at the reception. Girls often come to us who have experienced a “terrible shock”, when suddenly, before the standard period of the next menstruation, they see blood spots, and the fact of conception of a baby has already been confirmed. After all, any normal girl dreams of children and cannot even think about the possible loss of a child. Duphaston or Utrozhestan when planning pregnancy and during it can be crucial.

What is the hormone progesterone for?

Progesterone is the main hormone of expectant mothers. Surely you have heard the phrase “pregnancy hormone”. So this is about him.

Before pregnancy, its task is to prepare the endometrial layer in the uterus for the adoption of a fertilized egg.

A sufficient level of progesterone allows you to build it up thick, loose, nutritious. After fertilization of the egg, the future embryo reaches the inner cavity of the uterus and then must successfully implant into its wall. This happens with the help of chorionic villi, which literally grow into the “nutritional” layer of the endometrium prepared by progesterone, allowing the fetal egg to attach and “set up a connection” with the mother’s body. In the future, the placenta is formed from this part, which will produce progesterone throughout the pregnancy.

After the onset of pregnancy, it prevents uterine contractions, which prevents spontaneous abortion in the first trimester of pregnancy and inhibits the growth of follicles to allow the current pregnancy to develop. Once again, appreciate how smart nature is - after all, if fertilization would be possible during the onset of pregnancy and all embryos would develop in the uterus at different stages, interfering with each other)).

The doctor will prescribe you utrozhestan and duphaston in case of such a common problem as the threat of termination of pregnancy (both in the later stages and when the egg has just been fertilized and moves to the uterus), because they both contain progesterone. Utrozhestan is vegetable, and duphaston is synthetic.

Duphaston

The drug contains dydrogesterone, an artificial hormone progestogen, indicated in cases of insufficient production by the body itself. For primiparous women, it will have a preventive effect, and with the already existing experience of pregnancy, which resulted in a miscarriage, it will not allow the tragic outcome to recur. Or at least minimize the risk.

The drug is taken according to several schemes, depending on the purpose and indications:

• endometriosis - drink 1 tablet 2-3 times a day from the 5th to the 25th day of the cycle;
• infertility due to inferiority of the luteal phase - 1 tablet from the moment of ovulation;
• threatened miscarriage - 4 tablets at a time, then 1 piece 3 times a day until the symptoms disappear;
• habitual miscarriage - 1 piece twice a day at least until the 20th week of pregnancy, then the dose can be gradually reduced.

Reception regimens are very diverse, so you should determine the optimal dosage with a competent gynecologist. This usually requires a series of examinations. But an integrated approach will reduce the risk of pregnancy loss to a minimum.

Utrozhestan

The drug is presented in the form of round, soft gelatin capsules with liquid oily contents. The active substance is 100 or 200 mg of natural micronized progesterone in each capsule.

According to the instructions, the drug has 2 options for taking:

• drink in the evening before going to bed with enough water;
• suppositories are inserted deeply into the vagina, as close as possible to the cervix.

Both methods provide full absorption. But the introduction into the vagina has a directed action and allows you to achieve maximum concentration in the target area. For example, as an option, when the cervix is ​​not sufficiently closed when carrying a fetus (according to science - ICI, isthmic-cervical insufficiency).

An unpleasant side effect according to women's reviews is the release of liquid contents after rising to their feet for a long time. But, of course, this is a trifle compared with the therapeutic effect. To soften not the most pleasant sensations will allow ordinary daily pads.

Of the contraindications, there is a tendency to thrombosis and increased blood viscosity. Utrozhestan is used with caution in the presence of chronic diseases of the cardiovascular system.

conclusions

Yes, dufaston is a synthetic drug. However, it is this quality that makes it more preferable. The reconfiguration of the molecule has resulted in it being readily absorbed when taken orally. And the natural progesterone in utrozhestan is, at a minimum, a source of the possible development of allergic reactions.

Utrozhestan is usually prescribed by a doctor in the 1st trimester of pregnancy because of the convenience of vaginal capsules, especially when there is severe toxicosis, before vomiting. Duphaston can be prescribed at any stage of pregnancy if there is a threat of interruption or, according to the results of the tests, you have a clear progesterone deficiency.

Do not be alarmed if your doctor has prescribed you the simultaneous use of Duphaston and Utrozhestan. So he tries to minimize the likelihood of developing individual side effects associated with long-term use of hormonal drugs.

Most likely, the doctor will replace utrozhestan with duphaston at the end of the 2nd and 3rd trimesters of pregnancy, due to the negative effect on the liver.

At the time of pregnancy, when the placenta is fully formed and produces the required amount of progesterone itself, the doctor cancels Duphaston or Utrozhestan. But if you still have a threat of termination of pregnancy, or after the abolition of progesterone, there are pulling pains in the lower abdomen, uterine tone, continue to take the drugs further.

It is very important - hormonal drugs require a smooth withdrawal!

Withdrawal schemes are approximately the same - reducing the dose of the drug by half a tablet per week. But if the doctor assessed your condition and prescribed you to continue taking the drug, do not hesitate to ask all your questions - you do not need extra nerves and anxiety)).

If Duphaston and Utrozhestan stop taking abruptly, very serious consequences are possible - miscarriage in the early stages of pregnancy and premature birth in the late.

I can’t unequivocally answer the question of which drug is better than Duphaston or Utrozhestan. Your attending physician will prescribe one of them, taking into account your particular case, the specifics of the course of your particular pregnancy, and your specific comorbidities. Please do not self-prescribe drugs and dosages!

I suggest you watch a short video (06:19), in which Dr. Guzov (founder and director of the CIR) talks about progesterone preparations.

Based on all the information provided, it is up to you to decide what to take, for what and why. And you can get all the necessary answers to your questions from the observing gynecologist. Then there will be no reason to worry about the unknown and the baby will be born strong, healthy on time.

Preparations UTROZHESTAN and DUFASTON are usually prescribed to expectant mothers in the event of such a common problem as the threat of abortion. These drugs contain the hormone progesterone, under the influence of which important biological processes occur in the body of a woman, contributing to the successful bearing of the fetus.

The effect of progesterone on a woman's body is primarily aimed at providing favorable conditions for fertilization, attachment to the wall of the uterus and development of the fetal egg. The lack of production of this hormone often causes such an unfavorable episode of pregnancy as a miscarriage of the first trimester, because. it was during this period that the fetal egg had not yet attached to the uterus "tightly" and the mother's hormonal background had not formed completely and steadily.

The hormone progesterone refers to progestogens - female sex hormones produced in the ovaries. Even before fertilization, he prepares the uterus for the adoption of the embryo, stimulates the development of the mammary glands. With a lack of progesterone, the mother's body gives the wrong signal to the immune system, as a result of which the fetus is perceived by the body as a foreign agent, and this leads to detachment of the trophoblast - the "leaf" that feeds the fetus, from which the placenta should form in the future. As a result, a first trimester miscarriage can occur.

Progesterone began to be used to treat the threat of abortion as early as the 60s and 70s of the last century, but at the same time, its side effects on the child and mother were fully manifested, in particular, fetal malformations could not be avoided. Only with the development of high technologies and the possibilities of using molecular methods of synthesis, it was possible to obtain drugs that can qualitatively and safely deal with this unfavorable moment of pregnancy. These drugs include DUFASTON and UTROZHESTAN.

DUFASTON

DUFASTON is a potent progestogen hormone. which, in its molecular structure and pharmacological action, is close to endogenous (i.e., produced by the body) progesterone and, as a result, has a high affinity for progesterone receptors (structures that perceive the action of this hormone), i.e. fits them perfectly, like a key to a lock.

A "synthetic" change in the configuration of the molecule leads to the fact that DUFASTON is easily absorbed when taken orally. Unlike many progestogen hormones, DUFASTON is not a derivative of the male hormone testosterone - its structure differs from the structure of most synthetic progestogens, as a result of which the drug is devoid of their characteristic side effects. Unlike other synthetic gestagens, DUFASTON:

• does not cause the appearance of "female" signs in the male fetus and does not have a side effect on liver function and blood clotting;
• does not cause such manifestations as acne, coarsening of the voice, hirsutism (increased hairiness) and masculinization of the genital organs (enlargement of the clitoris) in the female fetus;
• does not cause changes in the lipid spectrum of blood and glucose concentration;
• does not negatively affect other organs of internal secretion.

The high safety of DUFASTON, confirmed by many years of experience in its use (there was not a single case of intrauterine malformation of the fetus), allows you to confidently use the drug as a hormonal support. In addition, compared with UTROZHESTAN, dydrogesterone does not have a sedative (calming) effect. Sometimes this factor contributes to the fact that this drug is chosen for treatment.

Due to the unique correspondence to natural progesterone, DUFASTON recreates the natural mechanisms of the normal course of pregnancy. The results of many studies on this drug are inspiring: the use of DU-FASTON reduces the incidence of placental insufficiency and premature birth by 2 times. And children are less likely to be underweight at birth, get a higher Apgar score (according to this scale, all newborns are evaluated, while paying attention to breathing, heartbeat, reflexes, skin, muscle tone). Newborns are less likely to experience hypoxic (i.e., associated with oxygen starvation) brain damage. The frequency of birth of healthy children increases by a third.

Of the side effects, in rare cases, uterine bleeding is possible (in this case, you should immediately consult a doctor). No other side effects have been identified with this drug.

The only significant contraindication for taking DUFASTON is hypersensitivity to the components of the drug, that is, individual intolerance.

DUFASTON (dydrogesterone) is a synthetic analogue of natural progesterone, UTROZHESTAN is natural progesterone. This is their main difference, which leads to some differences in the effects and use of these drugs.

Dydrogesterone is excreted in breast milk, therefore, if it is necessary to use the drug during lactation, the doctor raises the question of stopping breastfeeding.

DUFASTON is especially often used when using IVF technology - in vitro fertilization. Numerous observations show that the use of a synthetic drug in IVF is more effective than a natural natural analogue, although large international studies on this subject have not been published. Long-term use of this drug in a large dose is possible due to the advantages of DUFASTON - high stable availability to tissues and the absence of side effects.

UTROZHESTAN

UTROZHESTAN is the only progesterone in the world produced from vegetable raw materials. This drug is a natural micronized, i.e. produced in a special form, progesterone (hormone molecules are surrounded by peanut butter). It is produced in the form of capsules for oral (by mouth) and intravaginal (in suppositories) use.

This drug has a complete resemblance to the progesterone molecule, and it is this property that provides a number of unique effects that distinguish it from other drugs in this group. UTROZHESTAN fully possesses the properties of endogenous (produced in the body) progesterone. It promotes pregnancy, prepares the endometrium for egg implantation. UTROZHESTAN (like DUFASTON) does not change body weight and does not contribute to fluid retention in the body, does not affect lipid and carbohydrate metabolism and does not increase blood pressure.

The unique structure of the UTROZHESTAN molecule allows it to influence the exchange of male androgen hormones (and they are also present in women during pregnancy). which not only has a positive effect on the course of pregnancy, but also improves skin condition.

UTROZHESTAN also has a positive effect when a woman has an increased amount of male sex hormones (hyperandrogenism) due to the fact that this drug interacts in the body with the same receptors as androgens, i.e. competes with them.

Another unique mechanism for UTROZHESTAN to maintain and maintain pregnancy is its ability to suppress the effects of oxytocin (this hormone is also produced by the ovaries, and it is he who stimulates uterine contractions and leads to miscarriage). This effect of UTROZHESTAN is especially pronounced when taken orally.

The usual dose of UTROZHESTAN is 200-300 mg per day, while any of the two routes of administration of the drug can be used - intravaginal or oral. When eliminating the threat of abortion, the combination of intravaginal administration of UTROZHESTAN with oral administration is more preferable and effective. It is important to note that the initial dose of UTROZHESTAN in case of a threatened miscarriage is 400-600 mg at once, followed by a maintenance dose of 400-600 mg per day. If this therapy is ineffective, the dose of UTROZHESTAN can be increased to 800-1000 mg per day. But the appointment of treatment, as well as changing the dose, should be carried out only by a doctor, since this is a hormonal drug, and its overdose or lack in the body can end tragically for pregnancy. Cancellation of UTROZHESTAN or a change in its dose is carried out under the control of various indicators of pregnancy, including the concentration of progesterone in the blood: it changes smoothly during normal pregnancy - and cancellation should also occur without “bursts”.

Let's say a few words about the side effects that may occur when taking this drug. Like "own" progesterone, UTROZHESTAN slightly increases body temperature and has a calming and hypnotic effect, more pronounced when taken orally. When taking the drug inside, drowsiness and dizziness may also occur.

In case of serious liver diseases, oral administration of UTROGEST is contraindicated - it is recommended to switch to intravaginal use, since the drug is actively metabolized (processed) by the liver.

In conclusion, let me remind dear mothers that if a doctor prescribes any of the considered drugs to a pregnant woman, then this means a full and serious treatment, since it is associated with the intake of hormones, the minimum changes in the concentration of which in the blood (including without the knowledge of the doctor) in that or the other side can cross out both the efforts of the doctor and your pregnancy. Therefore, when taking these medicines, always keep a "hand on the pulse" - visit your doctor regularly and strictly follow his advice.

Women's health is largely influenced by the proper functioning of hormones. Progesterone is the most important component in the hormonal system of the body. If this hormone is not enough, malfunctions may occur in the reproductive system.

In such cases, gynecologists prescribe hormonal preparations containing progesterone, most often Utrozhestan or Duphaston.

Utrozhestan: properties and instructions

Utrozhestan contains progesterone, similar to the natural corpus luteum hormone produced by the ovaries or placenta (during pregnancy). It helps maintain the normal thickness of the walls of the endometrium, one of which is attached to the egg at the beginning of pregnancy.

Indications

The drug can be used orally or vaginally for progesterone-deficient conditions leading to abnormal functioning of the hormonal system:

In obstetrics, Utrozhestan is prescribed to women with a history of recurrent miscarriage, with a threat of abortion and premature birth.

Instructions for use

The dosage and frequency of use of Utrozhestan is determined by the cause of the hormone deficiency. This drug can be taken orally or vaginally.

• with a decrease in the luteal phase, the dosage is from 200 to 400 mg per day from the 16th to the 26th day of the cycle;
• before menopause (in combination with taking estrogen) 200 mg once a day for 12 days;
• in the postmenopausal period, 100-200 mg per day (in combination with estrogens). The individual dosage should be calculated by a specialist.

Vaginally:

• with the threat of miscarriage or premature birth, the daily dosage, divided into two doses at regular intervals, is usually 200-400 mg in the I and II trimesters of pregnancy;
• in the absence of progesterone production due to ovarian dysfunction in combination with estrogens, utrogestan is taken according to the doctor's prescriptions according to an individual scheme;
• in IVF, usually 200 to 600 mg per day is prescribed during the first 28 weeks of pregnancy;
• with functional disorders of the corpus luteum, take 200-300 mg per day from 17 to 27 days of the cycle; in case of pregnancy, the intake should be continued.

The final decision on taking the drug should be made by the doctor, based on the individual needs of the patient.

Side effects

Usually the drug is well tolerated by the body, however, in some cases, adverse effects may occur:

Reducing the dosage, taking the drug at bedtime, or switching to vaginal use will help eliminate weakness and dizziness.

The price of the drug

The cost of Utrozhestan varies from approximately 360 to 500 rubles, depending on the region and place of sale of the medication.

Dufaston: properties and instructions

The main component of Duphaston is dydrogesterone, a synthetic progesterone, similar in structure and properties to natural. With a lack of progesterone, Duphaston does not affect the suppression of ovulation.

Dydrogesterone promotes conception and successful pregnancy. During menopause, it improves the action of estrogens, while it does not increase blood clotting and does not destroy the liver, it is easily tolerated by the body.

Indications for use

Progesterone deficiency and related diseases (endometrial inflammation, premenstrual syndrome, painful menstruation, infertility, threatened miscarriage, various cycle disorders; menopause and menopause).

Duphaston may be prescribed by a doctor when planning a pregnancy to create the desired hormonal levels in the first trimester of gestation.

Instructions for use

Dufaston is taken orally one or more times a day (depending on the dosage and the appointment of a specialist) at the same time.

Cancellation of Duphaston during pregnancy is carried out gradually (reduce the dosage by 10 mg every three to four days). Otherwise, there is a risk of bleeding.

Side effects

Taking Duphaston as a hormonal drug can sometimes be associated with the development of undesirable effects:

• anemia;
• headache;
• minor violations of the liver;
• malaise;
• rarely - bleeding;
• skin itching and other allergic reactions.

Side effects when taking Duphaston are extremely rare, but if they are found, you should immediately consult a doctor.

The price of the drug

The cost of the drug Duphaston ranges from about 450 to 600 rubles, depending on where this medication is sold.

Comparative characteristics of the contraindications of drugs Duphaston and Utrozhestan

Like any hormonal drugs, Utrozhestan and Dufaston have a number of contraindications, which can be presented in the form of a table:

Obviously, Duphaston has fewer contraindications. This is due to the fact that dydrogesterone is more easily absorbed by the female body than natural progesterone, which, on the one hand, improves the functioning of the hormonal system, on the other hand, it can worsen the functioning of the gastrointestinal tract and liver.

Utrozhestan or Duphaston when planning pregnancy - which is better?

Utrozhestan is a complete analogue of female progesterone. It promotes the production of natural progesterone in women. However, you need to know that the drug Utrozhestan has a thickening effect on the circulatory system.

Duphaston is a synthetic analogue of progesterone. It completely or partially replaces the lack of natural female hormone. In any case, pregnancy planning is a serious step, so only a doctor, after a complete examination of the patient, can make the final choice in favor of one or another drug.

Utrozhestan or Duphaston - which is better during pregnancy and the threat of miscarriage?

Utrozhestan has more undesirable effects, it later began to be used in clinical practice, however, its natural composition and the possibility of vaginal administration often make a choice in favor of this drug.

During pregnancy, utrogestan reduces the tension of the muscles of the uterus, thereby removing its tone, which can cause a threatening abortion.

It must be understood that this or that drug may not be suitable for every pregnant woman. Therefore, when carrying a fetus and, even more so, when there is a threat of miscarriage, it is not recommended to take Duphaston or Utrozhestan without consulting a doctor.

Thus, both Duphaston and Utrozhestan are really good drugs with which you can defeat various female ailments.

1. Both medications contain progesterone, which is necessary for the normal functioning of the female reproductive system (including successful gestation).
2. Utrozhestan is made from vegetable raw materials, contains natural progesterone, and Dufaston is a synthetic drug, but it is thanks to this property that Dufaston is better absorbed by the body, which means it acts faster. Therefore, in situations that do not tolerate delay, doctors prefer Duphaston. If prolonged course treatment is required, Utrozhestan is more often prescribed, since it consists of a larger number of natural components.

Quite often, in gynecology, drugs such as Duphaston and Utrozhestan are used, which, in fact, are complete analogues. The choice in prescribing one or the other is made by the doctor, taking into account the characteristics of the pathology, as well as the individuality of each organism. That is why, many women have a question regarding what are the benefits of each of them, and which drug is better: Dufaston or Utrozhestan, if we compare them.

What is Duphaston and how does it affect the body?

Dufaston refers to hormonal drugs. The active substance of this drug is progesterone, the molecules of which are very similar in structure to those produced by the female body.

This fact ensures easy digestibility of Duphaston by the body. The drug is well absorbed. Unlike other similar drugs containing progesterone, Duphaston contains a hormone that is not a derivative of the male sex androgen, which eliminates the development of side effects such as male pattern hair growth, coarsening of the voice, etc.

Features of the drug Utrozhestan

The main difference between Utrozhestan and Duphaston is the fact that the first is the only drug that contains progesterone, produced exclusively from plant materials.

The drug is actively used in preparing a woman for pregnancy, before carrying out. This drug is involved in the preparation of the uterine endometrium for a fertilized egg into it, which eliminates the risk of its rejection.

What is better to choose: Utrozhestan or Dufaston?

Having learned how Dufaston differs from Utrozhestan, women are wondering which is more effective: the first or the second?

This question cannot be answered unambiguously. At its core, these 2 drugs are absolutely interchangeable and are prescribed based on medical preferences, or features of pathology. Among the disadvantages of Duphaston, one can single out the fact that the drug has a sedative effect, i.e. after its application tends to sleep.

In addition, the advantage of Utrozhestan can also be called the fact that it suppresses the action of oxytocin, and as a result reduces uterine tone.

When choosing a drug (Dufaston or Utrozhestan) during pregnancy, due to the above fact, the choice is made in favor of the latter. At the same time, the gynecologist indicates the dosage and frequency of administration, taking into account all the features of a particular pathology.